Articles Tagged with spinal cord injury

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A new study  finds that  cells derived from a patient’s own fat can help patients with spinal cord personal injury experience sensation and movement in the affected areas.

Stem cell therapies have been a major part of breakthrough research into spinal cord personal injury treatment over the past few years.  The findings of a recent study were published in the journal Nature Communications.  A  clinical trial on 10 patients found  significant improvement in functions like movement, after treatment with stem cells taken from the patient’s own fat.

Out of the 10 participants in the clinical trial, the researchers found that seven subjects exhibited significant improvements in their symptoms.  These  improvements were measured according to the American Spinal injury Association Impairment Scale.  The  researchers found improvements in sensation in the affected areas against testing with light touches.  Participants  also exhibited improvements in motor strength.  Patients with spinal cord personal injuries may also suffer from failure to control bowel and bladder movements and, in the study, participants were able to recover voluntary anal contractions which can be predictive of improvement in bowel functions.

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Patients who have suffered a spinal cord personal injury in an auto accident may experience  some improvement in their symptoms with the help of stem cell therapy using cells from their own fat.

Those findings come from a new study conducted by researchers at the Mayo Clinic. The findings of the study were published in the journal Nature Communications.  The study was conducted on 10 patients who had suffered a spinal cord personal injury.  The  researchers found in the study that the patients were able to recover some degree of sensation and movement in the areas affected  by their spinal injury.

The researchers extracted stem cells from fat from the patients’ thigh and abdomen areas.  They  expanded these stem cells  to 100 million cells which were then injected into the affected areas.  The researchers found that 7 out of the 10 patients showed improvement in their symptoms, including two out of three patients who had zero or minimal sensation below the site of their spinal cord injury.  Typically, only 5% of such patients manage to recover any kind of sensation or movement in their affected areas.  Moreover, the researchers say that there were no significant side effects as a result of the stem cell therapy.

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A spinal cord injury can result in loss of muscle to a larger extent than can be  attributed to lack of movement and mobility.   A new study points to one of the lesser known, but longer term consequences of a spinal cord injury after an auto accident.

A spinal cord injury is a serious personal injury that is caused when there is an injury to the spine during an auto accident, or motorcycle accident or pedestrian accident.  Spinal cord injuries may also be caused in slip and fall accidents.  The  degree and severity of the spinal cord injury can depend on the location of the vertebrae where the injury occurs.  Spinal cord injuries can result in loss of movement and mobility making it impossible for the person to  stand, walk and otherwise use his or her limbs.  These personal injuries  significantly alter a person’s life and  his ability to earn a living and live a  normal life after the personal injury.

A new study finds that there are long term consequences of a spinal injury that we may not be aware of.  The  study recently found that a spinal cord injury can cause significant muscle wastage in patients.  Some degree of muscle wastage in patients who have suffered a spinal cord injury is to be expected because of the lack of movement and exercise that can cause muscles to wither away.  According  to the study, however,  the kind of muscle wastage that a person with these injuries suffers cannot simply be explained away by lack of movement.  In fact, the researchers believe that it has more to do with the ability of the adrenal glands to receive nerve signals.

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Victims  of car accidents, motorcycle accidents and trucking accidents  who have suffered a spinal cord injury may look forward to a day when they can walk independently again thanks to a new breakthrough in research in the field.

Scientists  recently announced a breakthrough  in their attempts to regenerate axons in  persons who have suffered  a spinal cord injury.  The  breakthrough was announced by a team of scientists that included both Swiss and American  researchers. According to the team,  they found that redirecting  regenerated axons to their target regions was more effective in helping along the healing process and aided the recovery of the patient,  compared to random regrowth of axons.

Back in 2018, the team had identified that axons which are responsible for communicating transmissions among the nerve cells could be regrown after the damage.  However,  they found that even when the axons were regrown, it did not really lead to any marked or significant functional recovery for the patient.  Now,  however,  they say that they have found a way to redirect the regenerated axons to their target region, helping  restore functional movement.  The  researchers experimented on mice with spinal cord injury, and found that the mice were actually able to walk independently after the treatment.

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Spinal cord injuries are serious personal injuries that can be caused after an auto accident.  New  research finds that these injuries, in addition to permanently impacting a person’s day to day functioning, can significantly damage a person’s  immunity,  exposing the patient to the risk of life-threatening    infections.

A spinal cord injury can result from any kind of blow or serous impact to the spine.  The  impact does not have to include a fracture.  A spinal cord injury can also be caused by crushing injuries or dislocation of the spine. For example, when a person is thrown about the inside of a car during an auto accident, she or he could suffer serious personal injuries to the spine.  A  motorcycle rider who is thrown off a motorcycle  could land on the ground with force that is significant enough to  fracture his spine. In fact, spine injuries are common in motorcycle accidents when a person is separated from the motorcycle.

The risk of paralysis is very serious after a  spinal cord injury.  These  consequences of a spinal injury can also  have a long term impact on a person’s health.    A new study finds that a spinal injury may also trigger immunodeficiency syndrome.  This  condition can result in a loss of immunity, thereby exposing the person to the risk of infections. The study was conducted by researchers on 111 patients who had suffered spinal cord injury.  They found that soon after a spinal cord injury, the number of antibodies in the body dropped.  There  was also a deactivation of the monocytes or white blood cells that are responsible for staving off infections.

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Spinal cord injuries can have a devastating impact on a person’s life and livelihood.  These injuries can be permanent and may have no permanent cure.

Treatment for spinal cord injuries typically involves the management of decreased mobility and movement in patients. New studies recently, however, have shown a promising way forward in spinal injury treatment.

Scientists recently experimented on mice using an injectable therapy involving nanofibers to cover the damaged spinal tissue after the injury. The injections comprise of liquid nanogels that cover the damaged area, and create an environment that is very similar to the natural cellular environment. The nanofibers are able to mimic the natural movement of the cells, thereby promoting healing in these areas. The researchers found extraordinary results with the use of the therapy. After just about three to four weeks of the therapy, the mice were able to walk, and most of the damage was reversed.

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Spinal cord injuries can be devastating and have life long implications.   A traumatic spinal cord injury is difficult to recover from for most all individuals. However, frail victims of spinal cord injuries may have a much higher risk of adverse effects and complications than healthy individuals.  These complications can include greater occurrence of hospitalizations and death after the injury.

According to the results of a new study that was published in the Journal of Neurotrauma, frail victims of a spinal injury are at a higher risk of possibly life -threatening complications after the injury. The researchers identified spinal cord injury victims from between 2004 and 2016. The average median age of the patients was 50.3 years. Out of a total of 643 patients that were studied as part of the research, 77 percent were male. Falls were the leading cause of spinal injuries, with more than 60 percent of the patients, having suffered a spinal injury as the result of a slip and fall accident.

The researchers found that in patients below the age of 60 years, a person’s frail condition was a fairly reliable predictor of the number of adverse events, in-hospital mortality as well as length of hospital stay. In patients that were between 61 and 75 years of age, the frailty index also predicted the number of adverse events, length of hospital stay as well as in- hospital mortality. However, in patients above the age of 75, frailty did not predict any outcomes.

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